Targeted Alpha Therapy Approach to the Management of Pancreatic Cancer

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Targeted Alpha Therapy Approach to the Management of Pancreatic Cancer

Evidence for the efficacy of targeted alpha therapy for the control of pancreatic cancer in preclinical models is reviewed. Results are given for in vitro pancreatic cancer cells and clusters and micro-metastatic cancer lesions in vivo. Two complementary targeting vectors are examined. These are the C595 monoclonal antibody that targets the MUC1 antigen and the PAI2 ligand that targets the uPA ...

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ژورنال

عنوان ژورنال: Cancers

سال: 2011

ISSN: 2072-6694

DOI: 10.3390/cancers3021821